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TRPV4 enhances the synthesis of fatty acids to drive the progression of ovarian cancer through the calcium-mTORC1/SREBP1 signaling pathway

Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel activated by various stimuli, such as heat. A recent study reported that high expression of TRPV4 predicted a poor prognosis in ovarian cancer patients. This study demonstrated that TRPV4 was highly expressed in ovaria...

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Detalles Bibliográficos
Autores principales: Lin, Lan, Li, Xiao, Wu, Ai-Jia, Xiu, Jia-bin, Gan, Yu-Zheng, Yang, Xiao-mei, Ai, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637939/
https://www.ncbi.nlm.nih.gov/pubmed/37953947
http://dx.doi.org/10.1016/j.isci.2023.108226