Insulin-like growth factor binding protein-3 mediates hyperosmolar stress–induced mitophagy through the mechanistic target of rapamycin

Hyperosmolarity of the ocular surface triggers inflammation and pathological damage in dry eye disease (DED). In addition to a reduction in quality of life, DED causes vision loss and when severe, blindness. Mitochondrial dysfunction occurs as a consequence of hyperosmolar stress. We have previously...

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Detalles Bibliográficos
Autores principales: Stuard Sambhariya, Whitney, Trautmann, Ian J., Robertson, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637961/
https://www.ncbi.nlm.nih.gov/pubmed/37690686
http://dx.doi.org/10.1016/j.jbc.2023.105239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637961/
https://www.ncbi.nlm.nih.gov/pubmed/37690686
http://dx.doi.org/10.1016/j.jbc.2023.105239

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