Cargando…
Insulin-like growth factor binding protein-3 mediates hyperosmolar stress–induced mitophagy through the mechanistic target of rapamycin
Hyperosmolarity of the ocular surface triggers inflammation and pathological damage in dry eye disease (DED). In addition to a reduction in quality of life, DED causes vision loss and when severe, blindness. Mitochondrial dysfunction occurs as a consequence of hyperosmolar stress. We have previously...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637961/ https://www.ncbi.nlm.nih.gov/pubmed/37690686 http://dx.doi.org/10.1016/j.jbc.2023.105239 |