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Gene expression profiles (GEPs) of immuno-oncologic pathways as predictors of response to checkpoint inhibitors in advanced NSCLC

BACKGROUND: Immune checkpoint inhibitors (ICIs) revolutionized non-small-cell lung cancer (NSCLC) treatment. However, improving patients’ selection for this therapy is needed. Gene expression profile (GEP) is a promising biomarker tool. We assessed the predictive value of 48 onco-immune GEPs in an N...

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Detalles Bibliográficos
Autores principales: De Marchi, Pedro, Leal, Leticia Ferro, da Silva, Luciane Sussuchi, Cavagna, Rodrigo de Oliveira, da Silva, Flavio Augusto Ferreira, da Silva, Vinicius Duval, da Silva, Eduardo CA, Saito, Augusto O., de Lima, Vladmir C. Cordeiro, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638041/
https://www.ncbi.nlm.nih.gov/pubmed/37918166
http://dx.doi.org/10.1016/j.tranon.2023.101818