S100PBP is regulated by mutated KRAS and plays a tumour suppressor role in pancreatic cancer

We have previously shown that expression of S100PBP, an S100P binding partner, gradually decreases during progression of pancreatic ductal adenocarcinomas (PDAC). Here, we show that loss of S100PBP leads to oncogenic transformation of pancreatic cells; after deregulation of S100PBP expression, both...

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Detalles Bibliográficos
Autores principales: Srivastava, K., Lines, K. E., Jach, D., Crnogorac-Jurcevic, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638088/
https://www.ncbi.nlm.nih.gov/pubmed/37794133
http://dx.doi.org/10.1038/s41388-023-02851-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638088/
https://www.ncbi.nlm.nih.gov/pubmed/37794133
http://dx.doi.org/10.1038/s41388-023-02851-y

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