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S100PBP is regulated by mutated KRAS and plays a tumour suppressor role in pancreatic cancer
We have previously shown that expression of S100PBP, an S100P binding partner, gradually decreases during progression of pancreatic ductal adenocarcinomas (PDAC). Here, we show that loss of S100PBP leads to oncogenic transformation of pancreatic cells; after deregulation of S100PBP expression, both...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638088/ https://www.ncbi.nlm.nih.gov/pubmed/37794133 http://dx.doi.org/10.1038/s41388-023-02851-y |