PD-L1 regulates inflammatory programs of macrophages from human pluripotent stem cells

Programmed death ligand 1 (PD-L1) serves as a pivotal immune checkpoint in both the innate and adaptive immune systems. PD-L1 is expressed in macrophages in response to IFNγ. We examined whether PD-L1 might regulate macrophage development. We established PD-L1 KO (CD274(-/-)) human pluripotent stem...

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Detalles Bibliográficos
Autores principales: Cao, Handi, Xiang, Yang, Zhang, Shihui, Chao, Yiming, Guo, Jilong, Aurich, Theo, Ho, Joshua WK, Huang, Yuanhua, Liu, Pentao, Sugimura, Ryohichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638094/
https://www.ncbi.nlm.nih.gov/pubmed/37949473
http://dx.doi.org/10.26508/lsa.202302461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638094/
https://www.ncbi.nlm.nih.gov/pubmed/37949473
http://dx.doi.org/10.26508/lsa.202302461

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