Cargando…

Uncoupled evolution of the Polycomb system and deep origin of non-canonical PRC1

Polycomb group proteins, as part of the Polycomb repressive complexes, are essential in gene repression through chromatin compaction by canonical PRC1, mono-ubiquitylation of histone H2A by non-canonical PRC1 and tri-methylation of histone H3K27 by PRC2. Despite prevalent models emphasizing tight fu...

Descripción completa

Detalles Bibliográficos
Autores principales: de Potter, Bastiaan, Raas, Maximilian W. D., Seidl, Michael F., Verrijzer, C. Peter, Snel, Berend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638273/
https://www.ncbi.nlm.nih.gov/pubmed/37949928
http://dx.doi.org/10.1038/s42003-023-05501-x