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Tumor microenvironment heterogeneity in bladder cancer identifies biologically distinct subtypes predicting prognosis and anti-PD-L1 responses

Bladder cancer (BCa) is heterogeneous in the tumour microenvironment (TME). However, the role of the TME in BCa in modulating the response to immunotherapy has not been fully explored. We therefore analysed fractions of immune cells using CIBERSORTx and clustered BCa into subtypes. We also analyzed...

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Detalles Bibliográficos
Autores principales: Li, YaFei, Liu, Yi, Kang, Zhengjun, Guo, Jianhua, Liu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638294/
https://www.ncbi.nlm.nih.gov/pubmed/37949863
http://dx.doi.org/10.1038/s41598-023-44028-3