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Calculation of exact Shapley values for explaining support vector machine models using the radial basis function kernel

Machine learning (ML) algorithms are extensively used in pharmaceutical research. Most ML models have black-box character, thus preventing the interpretation of predictions. However, rationalizing model decisions is of critical importance if predictions should aid in experimental design. Accordingly...

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Detalles Bibliográficos
Autores principales: Mastropietro, Andrea, Feldmann, Christian, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638308/
https://www.ncbi.nlm.nih.gov/pubmed/37949930
http://dx.doi.org/10.1038/s41598-023-46930-2