PRMT2 promotes HIV-1 latency by preventing nucleolar exit and phase separation of Tat into the Super Elongation Complex

The HIV-1 Tat protein hijacks the Super Elongation Complex (SEC) to stimulate viral transcription and replication. However, the mechanisms underlying Tat activation and inactivation, which mediate HIV-1 productive and latent infection, respectively, remain incompletely understood. Here, through a ta...

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Detalles Bibliográficos
Autores principales: Jin, Jiaxing, Bai, Hui, Yan, Han, Deng, Ting, Li, Tianyu, Xiao, Ruijing, Fan, Lina, Bai, Xue, Ning, Hanhan, Liu, Zhe, Zhang, Kai, Wu, Xudong, Liang, Kaiwei, Ma, Ping, Gao, Xin, Hu, Deqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638354/
https://www.ncbi.nlm.nih.gov/pubmed/37949879
http://dx.doi.org/10.1038/s41467-023-43060-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638354/
https://www.ncbi.nlm.nih.gov/pubmed/37949879
http://dx.doi.org/10.1038/s41467-023-43060-1

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