Deep learning-based image analysis identifies a DAT-negative subpopulation of dopaminergic neurons in the lateral Substantia nigra

Here we present a deep learning-based image analysis platform (DLAP), tailored to autonomously quantify cell numbers, and fluorescence signals within cellular compartments, derived from RNAscope or immunohistochemistry. We utilised DLAP to analyse subtypes of tyrosine hydroxylase (TH)-positive dopam...

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Detalles Bibliográficos
Autores principales: Burkert, Nicole, Roy, Shoumik, Häusler, Max, Wuttke, Dominik, Müller, Sonja, Wiemer, Johanna, Hollmann, Helene, Oldrati, Marvin, Ramirez-Franco, Jorge, Benkert, Julia, Fauler, Michael, Duda, Johanna, Goaillard, Jean-Marc, Pötschke, Christina, Münchmeyer, Moritz, Parlato, Rosanna, Liss, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638391/
https://www.ncbi.nlm.nih.gov/pubmed/37950046
http://dx.doi.org/10.1038/s42003-023-05441-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638391/
https://www.ncbi.nlm.nih.gov/pubmed/37950046
http://dx.doi.org/10.1038/s42003-023-05441-6

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