MELK promotes HCC carcinogenesis through modulating cuproptosis-related gene DLAT-mediated mitochondrial function

Cuproptosis caused by copper overload is mediated by a novel regulatory mechanism that differs from previously documented mechanisms regulating cell death. Cells dependent on mitochondrial respiration showed increased sensitivity to a copper ionophore elesclomol that induced cuproptosis. Maternal em...

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Detalles Bibliográficos
Autores principales: Li, Zhipeng, Zhou, Huaxin, Zhai, Xiangyu, Gao, Lin, Yang, Mengfan, An, Baokun, Xia, Tong, Du, Gang, Li, Xiaoming, Wang, Wei, Jin, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638394/
https://www.ncbi.nlm.nih.gov/pubmed/37949877
http://dx.doi.org/10.1038/s41419-023-06264-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638394/
https://www.ncbi.nlm.nih.gov/pubmed/37949877
http://dx.doi.org/10.1038/s41419-023-06264-3

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