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MELK promotes HCC carcinogenesis through modulating cuproptosis-related gene DLAT-mediated mitochondrial function
Cuproptosis caused by copper overload is mediated by a novel regulatory mechanism that differs from previously documented mechanisms regulating cell death. Cells dependent on mitochondrial respiration showed increased sensitivity to a copper ionophore elesclomol that induced cuproptosis. Maternal em...
Autores principales: | Li, Zhipeng, Zhou, Huaxin, Zhai, Xiangyu, Gao, Lin, Yang, Mengfan, An, Baokun, Xia, Tong, Du, Gang, Li, Xiaoming, Wang, Wei, Jin, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638394/ https://www.ncbi.nlm.nih.gov/pubmed/37949877 http://dx.doi.org/10.1038/s41419-023-06264-3 |
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