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Drug screen identifies verteporfin as a regulator of lipid metabolism in macrophage foam cells
Arterial macrophage foam cells are filled with cholesterol ester (CE) stored in cytosolic lipid droplets (LDs). Foam cells are central players in progression of atherosclerosis as regulators of lipid metabolism and inflammation, two major driving forces of atherosclerosis development. Thus, foam cel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638409/ https://www.ncbi.nlm.nih.gov/pubmed/37949969 http://dx.doi.org/10.1038/s41598-023-46467-4 |