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IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages

In cardiovascular disease, pathological and protective roles are reported for the Th2 cytokines IL-4 and IL-13, respectively. We hypothesised that differential effects on macrophage function are responsible. Type I and II receptor subunit (IL-2Rγ, IL-4Rα and IL-13Rα1) and M2 marker (MRC-1, CCL18, CC...

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Detalles Bibliográficos
Autores principales: Scott, Tara E., Lewis, Caitlin V., Zhu, Mingyu, Wang, Chao, Samuel, Chrishan S., Drummond, Grant R., Kemp-Harper, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638413/
https://www.ncbi.nlm.nih.gov/pubmed/37949903
http://dx.doi.org/10.1038/s41598-023-46237-2