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Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing

Alterations in mTOR signalling molecules, including RICTOR amplification, have been previously described in many cancers, particularly associated with poor prognosis. In this study, RICTOR copy number variation (CNV) results of diagnostic next-generation sequencing (NGS) were analysed in 420 various...

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Detalles Bibliográficos
Autores principales: Sztankovics, Dániel, Krencz, Ildikó, Moldvai, Dorottya, Dankó, Titanilla, Nagy, Ákos, Nagy, Noémi, Bedics, Gábor, Rókusz, András, Papp, Gergő, Tőkés, Anna-Mária, Pápay, Judit, Sápi, Zoltán, Dezső, Katalin, Bödör, Csaba, Sebestyén, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638425/
https://www.ncbi.nlm.nih.gov/pubmed/37949943
http://dx.doi.org/10.1038/s41598-023-46927-x