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Drug discovery by targeting the protein–protein interactions involved in autophagy
Autophagy is a cellular process in which proteins and organelles are engulfed in autophagosomal vesicles and transported to the lysosome/vacuole for degradation. Protein–protein interactions (PPIs) play a crucial role at many stages of autophagy, which present formidable but attainable targets for a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638514/ https://www.ncbi.nlm.nih.gov/pubmed/37969735 http://dx.doi.org/10.1016/j.apsb.2023.07.016 |