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Drug discovery by targeting the protein–protein interactions involved in autophagy

Autophagy is a cellular process in which proteins and organelles are engulfed in autophagosomal vesicles and transported to the lysosome/vacuole for degradation. Protein–protein interactions (PPIs) play a crucial role at many stages of autophagy, which present formidable but attainable targets for a...

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Detalles Bibliográficos
Autores principales: Xiang, Honggang, Zhou, Mi, Li, Yan, Zhou, Lu, Wang, Renxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638514/
https://www.ncbi.nlm.nih.gov/pubmed/37969735
http://dx.doi.org/10.1016/j.apsb.2023.07.016