Function, mechanism and drug discovery of ubiquitin and ubiquitin-like modification with multiomics profiling for cancer therapy

Ubiquitin (Ub) and ubiquitin-like (Ubl) pathways are critical post-translational modifications that determine whether functional proteins are degraded or activated/inactivated. To date, >600 associated enzymes have been reported that comprise a hierarchical task network (e.g., E1–E2–E3 cascade en...

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Detalles Bibliográficos
Autores principales: Jiang, Yanyu, Ni, Shuaishuai, Xiao, Biying, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638515/
https://www.ncbi.nlm.nih.gov/pubmed/37969742
http://dx.doi.org/10.1016/j.apsb.2023.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638515/
https://www.ncbi.nlm.nih.gov/pubmed/37969742
http://dx.doi.org/10.1016/j.apsb.2023.07.019

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