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Carbazole and tetrahydro-carboline derivatives as dopamine D(3) receptor antagonists with the multiple antipsychotic-like properties

Dopamine D(3) receptor (D(3)R) is implicated in multiple psychotic symptoms. Increasing the D(3)R selectivity over dopamine D(2) receptor (D(2)R) would facilitate the antipsychotic treatments. Herein, novel carbazole and tetrahydro-carboline derivatives were reported as D(3)R selective ligands. Thro...

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Detalles Bibliográficos
Autores principales: Li, Zhongtang, Fang, Fan, Li, Yiyan, Lv, Xuehui, Zheng, Ruqiu, Jiao, Peili, Wang, Yuxi, Zhu, Guiwang, Jin, Zefang, Xu, Xiangqing, Qiu, Yinli, Zhang, Guisen, Li, Zhongjun, Liu, Zhenming, Zhang, Liangren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638516/
https://www.ncbi.nlm.nih.gov/pubmed/37969740
http://dx.doi.org/10.1016/j.apsb.2023.07.024