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Carbazole and tetrahydro-carboline derivatives as dopamine D(3) receptor antagonists with the multiple antipsychotic-like properties
Dopamine D(3) receptor (D(3)R) is implicated in multiple psychotic symptoms. Increasing the D(3)R selectivity over dopamine D(2) receptor (D(2)R) would facilitate the antipsychotic treatments. Herein, novel carbazole and tetrahydro-carboline derivatives were reported as D(3)R selective ligands. Thro...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638516/ https://www.ncbi.nlm.nih.gov/pubmed/37969740 http://dx.doi.org/10.1016/j.apsb.2023.07.024 |