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Preclinical assessment of IL-1β primed human umbilical cord mesenchymal stem cells for tendon functional repair through TGF-β/IL-10 signaling

BACKGROUND: Inadequate repair capacity and disturbed immune compartments are the main pathological causes of tendinopathy. Transplantation of mesenchymal stem cells (MSCs) become an effective clinic option to alleviate tendinopathy. Interleukin-1β (IL-1β) could confer on MSCs enhanced immunoregulato...

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Detalles Bibliográficos
Autores principales: Wang, Shikun, Yao, Zhixiao, Chen, Lei, Li, Juehong, Chen, Shuai, Fan, Cunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638607/
https://www.ncbi.nlm.nih.gov/pubmed/37954299
http://dx.doi.org/10.1016/j.heliyon.2023.e21411