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Human Wharton’s jelly-derived mesenchymal stromal cells promote bone formation in immunodeficient mice when administered into a bone microenvironment

BACKGROUND: Wharton’s Jelly (WJ) Mesenchymal Stromal Cells (MSC) have emerged as an attractive allogeneic therapy for a number of indications, except for bone-related conditions requiring new tissue formation. This may be explained by the apparent recalcitrance of MSC,WJ to differentiate into the os...

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Detalles Bibliográficos
Autores principales: Cabrera-Pérez, Raquel, Ràfols-Mitjans, Alexis, Roig-Molina, Ángela, Beltramone, Silvia, Vives, Joaquim, Batlle-Morera, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638709/
https://www.ncbi.nlm.nih.gov/pubmed/37950242
http://dx.doi.org/10.1186/s12967-023-04672-9