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High expression of CDKN2A is associated with poor prognosis in colorectal cancer and may guide PD-1-mediated immunotherapy

BACKGROUND: Colorectal cancer (CRC) is one of the most common malignancies worldwide. Immunotherapy targeting the programmed death protein 1(PD-1) and its ligand (PD-L1), is a promising treatment option for many cancers, but has exhibited poor therapeutic efficacy in CRC. This study aimed to identif...

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Detalles Bibliográficos
Autores principales: Dong, Yuying, Zheng, Mingming, Wang, Xiaoxuan, Yu, Chenyue, Qin, Tiantian, Shen, Xuning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638725/
https://www.ncbi.nlm.nih.gov/pubmed/37950153
http://dx.doi.org/10.1186/s12885-023-11603-w