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ATACAmp: a tool for detecting ecDNA/HSRs from bulk and single-cell ATAC-seq data

BACKGROUND: High oncogene expression in cancer cells is a major cause of rapid tumor progression and drug resistance. Recent cancer genome research has shown that oncogenes as well as regulatory elements can be amplified in the form of extrachromosomal DNA (ecDNA) or subsequently integrated into chr...

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Detalles Bibliográficos
Autores principales: Cheng, Hansen, Ma, Wenhao, Wang, Kun, Chu, Han, Bao, Guangchao, Liao, Yu, Yuan, Yawen, Gou, Yixiong, Dong, Liting, Yang, Jian, Cai, Haoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638764/
https://www.ncbi.nlm.nih.gov/pubmed/37950200
http://dx.doi.org/10.1186/s12864-023-09792-6