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ATACAmp: a tool for detecting ecDNA/HSRs from bulk and single-cell ATAC-seq data
BACKGROUND: High oncogene expression in cancer cells is a major cause of rapid tumor progression and drug resistance. Recent cancer genome research has shown that oncogenes as well as regulatory elements can be amplified in the form of extrachromosomal DNA (ecDNA) or subsequently integrated into chr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638764/ https://www.ncbi.nlm.nih.gov/pubmed/37950200 http://dx.doi.org/10.1186/s12864-023-09792-6 |