Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway

Spinal cord injury (SCI) can prompt an immediate disruption to the blood–spinal cord barrier (BSCB). Restoring the integrity of this barrier is vital for the recovery of neurological function post-SCI. The UTX protein, a histone demethylase, has been shown in previous research to promote vascular re...

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Detalles Bibliográficos
Autores principales: Xie, Yong, Luo, Zixiang, Peng, Wei, Liu, Yudong, Yuan, Feifei, Xu, Jiaqi, Sun, Yi, Lu, Hongbin, Wu, Tianding, Jiang, Liyuan, Hu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638785/
https://www.ncbi.nlm.nih.gov/pubmed/37951955
http://dx.doi.org/10.1186/s12974-023-02936-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638785/
https://www.ncbi.nlm.nih.gov/pubmed/37951955
http://dx.doi.org/10.1186/s12974-023-02936-1

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