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Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway
Spinal cord injury (SCI) can prompt an immediate disruption to the blood–spinal cord barrier (BSCB). Restoring the integrity of this barrier is vital for the recovery of neurological function post-SCI. The UTX protein, a histone demethylase, has been shown in previous research to promote vascular re...
Autores principales: | Xie, Yong, Luo, Zixiang, Peng, Wei, Liu, Yudong, Yuan, Feifei, Xu, Jiaqi, Sun, Yi, Lu, Hongbin, Wu, Tianding, Jiang, Liyuan, Hu, Jianzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638785/ https://www.ncbi.nlm.nih.gov/pubmed/37951955 http://dx.doi.org/10.1186/s12974-023-02936-1 |
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