Characterization of amiodarone action on currents in hERG-T618 gain-of-function mutations

The purpose of this study was to determine the effect of amiodarone (Ami) on hERG-T618I currents in HEK293 cells. A transient transfection method was used to transfer hERG-T618I and hERG wild-type (WT) channel plasmids into HEK293 cells. An extracellular local perfusion method was used for administr...

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Detalles Bibliográficos
Autores principales: Lin, Min, Li, Cuiyun, Lin, Chao, Xiong, Shangquan, Xue, Qiao, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638844/
https://www.ncbi.nlm.nih.gov/pubmed/37954102
http://dx.doi.org/10.1515/biol-2022-0749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638844/
https://www.ncbi.nlm.nih.gov/pubmed/37954102
http://dx.doi.org/10.1515/biol-2022-0749

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