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BIBR1532 inhibits proliferation and enhances apoptosis in multiple myeloma cells by reducing telomerase activity

BACKGROUND: Multiple myeloma (MM) is a rare haematological disorder with few therapeutic options. BIBR1532, a telomerase inhibitor, is widely used in cancer treatment and has promising outcomes. In this study, we investigated the efficacy and mechanism of action of BIBR1532 in MM. METHODS: K562 and...

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Detalles Bibliográficos
Autores principales: Zhang, Yuefeng, Yang, Xinxin, Zhou, Hangqun, Yao, Guoli, Zhou, Li, Qian, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10638922/
https://www.ncbi.nlm.nih.gov/pubmed/37953768
http://dx.doi.org/10.7717/peerj.16404