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Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in db/db mice

Endothelial cells play a key role in maintaining homeostasis and are deranged in many disease processes, including fibrotic conditions. Absence of the endothelial glucocorticoid receptor (GR) has been shown to accelerate diabetic kidney fibrosis in part through upregulation of Wnt signaling. The db/...

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Detalles Bibliográficos
Autores principales: Srivastava, Swayam Prakash, Goodwin, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639025/
https://www.ncbi.nlm.nih.gov/pubmed/37589053
http://dx.doi.org/10.1152/ajprenal.00105.2023