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The unique structural and functional characteristics of glomerular endothelial cell fenestrations and their potential as a therapeutic target in kidney disease

Glomerular endothelial cell (GEnC) fenestrations are a critical component of the glomerular filtration barrier. Their unique nondiaphragmed structure is key to their function in glomerular hydraulic permeability, and their aberration in disease can contribute to loss of glomerular filtration functio...

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Detalles Bibliográficos
Autores principales: Finch, Natalie C., Neal, Chris R., Welsh, Gavin I., Foster, Rebecca R., Satchell, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639027/
https://www.ncbi.nlm.nih.gov/pubmed/37471420
http://dx.doi.org/10.1152/ajprenal.00036.2023