BRCA1–BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes

Chromatin association of the BRCA1–BARD1 heterodimer is critical to promote homologous recombination repair of DNA double-strand breaks (DSBs) in S/G2. How the BRCA1–BARD1 complex interacts with chromatin that contains both damage induced histone H2A ubiquitin and inhibitory H4K20 methylation is not...

Descripción completa

Detalles Bibliográficos
Autores principales: Burdett, Hayden, Foglizzo, Martina, Musgrove, Laura J, Kumar, Dhananjay, Clifford, Gillian, Campbell, Lisa J, Heath, George R, Zeqiraj, Elton, Wilson, Marcus D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639053/
https://www.ncbi.nlm.nih.gov/pubmed/37823591
http://dx.doi.org/10.1093/nar/gkad793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639053/
https://www.ncbi.nlm.nih.gov/pubmed/37823591
http://dx.doi.org/10.1093/nar/gkad793

Ejemplares similares