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BRCA1–BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes

Chromatin association of the BRCA1–BARD1 heterodimer is critical to promote homologous recombination repair of DNA double-strand breaks (DSBs) in S/G2. How the BRCA1–BARD1 complex interacts with chromatin that contains both damage induced histone H2A ubiquitin and inhibitory H4K20 methylation is not...

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Detalles Bibliográficos
Autores principales:	Burdett, Hayden, Foglizzo, Martina, Musgrove, Laura J, Kumar, Dhananjay, Clifford, Gillian, Campbell, Lisa J, Heath, George R, Zeqiraj, Elton, Wilson, Marcus D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639053/ https://www.ncbi.nlm.nih.gov/pubmed/37823591 http://dx.doi.org/10.1093/nar/gkad793

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