Immunoprecipitation of RNA–DNA hybrid interacting proteins in Trypanosoma brucei reveals conserved and novel activities, including in the control of surface antigen expression needed for immune evasion by antigenic variation

RNA–DNA hybrids are epigenetic features of genomes that provide a diverse and growing range of activities. Understanding of these functions has been informed by characterising the proteins that interact with the hybrids, but all such analyses have so far focused on mammals, meaning it is unclear if...

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Detalles Bibliográficos
Autores principales: Girasol, Mark J, Briggs, Emma M, Marques, Catarina A, Batista, José M, Beraldi, Dario, Burchmore, Richard, Lemgruber, Leandro, McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639054/
https://www.ncbi.nlm.nih.gov/pubmed/37843098
http://dx.doi.org/10.1093/nar/gkad836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639054/
https://www.ncbi.nlm.nih.gov/pubmed/37843098
http://dx.doi.org/10.1093/nar/gkad836

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