Systematic sequence engineering enhances the induction strength of the glucose-regulated GTH1 promoter of Komagataella phaffii

The promoter of the high-affinity glucose transporter Gth1 (P(GTH1)) is tightly repressed on glucose and glycerol surplus, and strongly induced in glucose-limitation, thus enabling regulated methanol-free production processes in the yeast production host Komagataella phaffii. To further improve this...

Descripción completa

Detalles Bibliográficos
Autores principales: Flores-Villegas, Mirelle, Rebnegger, Corinna, Kowarz, Viktoria, Prielhofer, Roland, Mattanovich, Diethard, Gasser, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639056/
https://www.ncbi.nlm.nih.gov/pubmed/37791854
http://dx.doi.org/10.1093/nar/gkad752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639056/
https://www.ncbi.nlm.nih.gov/pubmed/37791854
http://dx.doi.org/10.1093/nar/gkad752

Ejemplares similares