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Identification and quantification of small exon-containing isoforms in long-read RNA sequencing data

Small exons are pervasive in transcriptomes across organisms, and their quantification in RNA isoforms is crucial for understanding gene functions. Although long-read RNA-seq based on Oxford Nanopore Technologies (ONT) offers the advantage of covering transcripts in full length, its lower base accur...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Zhu, Chenchen, Steinmetz, Lars M, Wei, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639058/
https://www.ncbi.nlm.nih.gov/pubmed/37843096
http://dx.doi.org/10.1093/nar/gkad810