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An ATP-independent role for Prp16 in promoting aberrant splicing

The spliceosome is assembled through a step-wise process of binding and release of its components to and from the pre-mRNA. The remodeling process is facilitated by eight DExD/H-box RNA helicases, some of which have also been implicated in splicing fidelity control. In this study, we unveil a contra...

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Detalles Bibliográficos
Autores principales: Chung, Che-Sheng, Wai, Hsu Lei, Kao, Ching-Yang, Cheng, Soo-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639067/
https://www.ncbi.nlm.nih.gov/pubmed/37858289
http://dx.doi.org/10.1093/nar/gkad861