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Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities

Gene regulation plays a critical role in the cellular processes that underlie human health and disease. The regulatory relationship between transcription factors (TFs), key regulators of gene expression, and their target genes, the so called TF regulons, can be coupled with computational algorithms...

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Detalles Bibliográficos
Autores principales: Müller-Dott, Sophia, Tsirvouli, Eirini, Vazquez, Miguel, Ramirez Flores, Ricardo O, Badia-i-Mompel, Pau, Fallegger, Robin, Türei, Dénes, Lægreid, Astrid, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639077/
https://www.ncbi.nlm.nih.gov/pubmed/37843125
http://dx.doi.org/10.1093/nar/gkad841