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Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities
Gene regulation plays a critical role in the cellular processes that underlie human health and disease. The regulatory relationship between transcription factors (TFs), key regulators of gene expression, and their target genes, the so called TF regulons, can be coupled with computational algorithms...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639077/ https://www.ncbi.nlm.nih.gov/pubmed/37843125 http://dx.doi.org/10.1093/nar/gkad841 |