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Single-molecule FRET observes opposing effects of urea and TMAO on structurally similar meso- and thermophilic riboswitch RNAs

Bacteria live in a broad range of environmental temperatures that require adaptations of their RNA sequences to maintain function. Riboswitches are regulatory RNAs that change conformation upon typically binding metabolite ligands to control bacterial gene expression. The paradigmatic small class-I...

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Detalles Bibliográficos
Autores principales: Hou, Qian, Chatterjee, Surajit, Lund, Paul E, Suddala, Krishna C, Walter, Nils G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639078/
https://www.ncbi.nlm.nih.gov/pubmed/37855661
http://dx.doi.org/10.1093/nar/gkad866