Drosha-dependent microRNAs modulate FUS-mediated neurodegeneration in vivo

Mutations in the Fused in Sarcoma (FUS) gene cause the familial and progressive form of amyotrophic lateral sclerosis (ALS). FUS is a nuclear RNA-binding protein involved in RNA processing and the biogenesis of a specific set of microRNAs. Here we report that Drosha and two previously uncharacterize...

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Detalles Bibliográficos
Autores principales: Kour, Sukhleen, Fortuna, Tyler, Anderson, Eric N, Mawrie, Darilang, Bilstein, Jessica, Sivasubramanian, Ramakrishnan, Ward, Caroline, Roy, Rishit, Rajasundaram, Dhivyaa, Sterneckert, Jared, Pandey, Udai Bhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639082/
https://www.ncbi.nlm.nih.gov/pubmed/37791873
http://dx.doi.org/10.1093/nar/gkad774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639082/
https://www.ncbi.nlm.nih.gov/pubmed/37791873
http://dx.doi.org/10.1093/nar/gkad774

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