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Detection of queuosine and queuosine precursors in tRNAs by direct RNA sequencing

Queuosine (Q) is a complex tRNA modification found in bacteria and eukaryotes at position 34 of four tRNAs with a GUN anticodon, and it regulates the translational efficiency and fidelity of the respective codons that differ at the Wobble position. In bacteria, the biosynthesis of Q involves two pre...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Piechotta, Michael, Naarmann-de Vries, Isabel, Dieterich, Christoph, Ehrenhofer-Murray, Ann E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639084/
https://www.ncbi.nlm.nih.gov/pubmed/37811872
http://dx.doi.org/10.1093/nar/gkad826