Functional evaluation of complement factor I variants by immunoassays and SDS-PAGE

Factor I (FI) is an essential regulator of the complement system. Together with co-factors, FI degrades C3b, which inhibits further complement activation. Genetic mutations in FI are associated with pathological conditions like age-related macular degeneration and atypical hemolytic uremic syndome....

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Detalles Bibliográficos
Autores principales: Gerogianni, Alexandra, Baas, Laura M., Sjöström, Dick J., van de Kar, Nicole C. A. J., Pullen, Marit, van de Peppel, Siem J., Nilsson, Per H., van den Heuvel, Lambertus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639126/
https://www.ncbi.nlm.nih.gov/pubmed/37954579
http://dx.doi.org/10.3389/fimmu.2023.1279612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639126/
https://www.ncbi.nlm.nih.gov/pubmed/37954579
http://dx.doi.org/10.3389/fimmu.2023.1279612

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