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The role and mechanisms of macrophage polarization and hepatocyte pyroptosis in acute liver failure

Acute liver failure (ALF) is a severe liver disease caused by disruptions in the body’s immune microenvironment. In the early stages of ALF, Kupffer cells (KCs) become depleted and recruit monocytes derived from the bone marrow or abdomen to replace the depleted macrophages entering the liver. These...

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Detalles Bibliográficos
Autores principales: Xie, Dan, Ouyang, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10639160/
https://www.ncbi.nlm.nih.gov/pubmed/37954583
http://dx.doi.org/10.3389/fimmu.2023.1279264