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Hypothyroidism increases angiotensinogen gene expression associated with vascular smooth muscle cells cholesterol metabolism dysfunction and aorta remodeling in Psammomys obesus

It has been previously shown that clinical cardiovascular manifestations can be caused by mild changes in thyroid function. However, the implication of angiotensinogen (Agt) and vascular smooth muscle cells (VSMCs) dysfunction in the pathophysiology of cardiovascular manifestations in hypothyroidism...

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Detalles Bibliográficos
Autores principales: Neggazi, Samia, Hamlat, Nadjiba, Berdja, Sihem, Boumaza, Saliha, Smail, Leila, Beylot, Michel, Aouichat-Bouguerra, Souhila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640574/
https://www.ncbi.nlm.nih.gov/pubmed/37951959
http://dx.doi.org/10.1038/s41598-023-46899-y