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The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization
RIG-I is an essential innate immune receptor that responds to infection by RNA viruses. The RIG-I signaling cascade is mediated by a series of post-translational modifications, the most important of which is ubiquitination of the RIG-I Caspase Recruitment Domains (CARDs) by E3 ligase Riplet. This is...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640585/ https://www.ncbi.nlm.nih.gov/pubmed/37951994 http://dx.doi.org/10.1038/s41467-023-42982-0 |