SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase

SARS-CoV-2 infection requires Spike protein-mediated fusion between the viral and cellular membranes. The fusogenic activity of Spike depends on its post-translational lipid modification by host S-acyltransferases, predominantly ZDHHC20. Previous observations indicate that SARS-CoV-2 infection augme...

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Detalles Bibliográficos
Autores principales: S. Mesquita, Francisco, Abrami, Laurence, Bracq, Lucie, Panyain, Nattawadee, Mercier, Vincent, Kunz, Béatrice, Chuat, Audrey, Carlevaro-Fita, Joana, Trono, Didier, van der Goot, F. Gisou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
https://www.ncbi.nlm.nih.gov/pubmed/37952051
http://dx.doi.org/10.1038/s41467-023-43027-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
https://www.ncbi.nlm.nih.gov/pubmed/37952051
http://dx.doi.org/10.1038/s41467-023-43027-2

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