Nanomedicine-based co-delivery of a calcium channel inhibitor and a small molecule targeting CD47 for lung cancer immunotherapy

Pro-tumoral macrophages in lung tumors present a significant challenge in immunotherapy. Here, we introduce a pH-responsive nanomedicine approach for activating anti-tumoral macrophages and dendritic cells. Using a layered double hydroxide nanosheet carrier, we co-deliver a T-type calcium channel in...

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Detalles Bibliográficos
Autores principales: Guo, Yuedong, Bao, Qunqun, Hu, Ping, Shi, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640620/
https://www.ncbi.nlm.nih.gov/pubmed/37951973
http://dx.doi.org/10.1038/s41467-023-42972-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640620/
https://www.ncbi.nlm.nih.gov/pubmed/37951973
http://dx.doi.org/10.1038/s41467-023-42972-2

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