The Na(+)–H(+ )exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

INTRODUCTION: An increasing body of evidence shows that the tumour microenvironment is essential in driving neoplastic progression. The low serum component of this microenvironment stimulates motility/invasion in human breast cancer cells via activation of the Na(+)–H(+ )exchanger (NHE) isoform 1, b...

Descripción completa

Detalles Bibliográficos
Autores principales: Paradiso, Angelo, Cardone, Rosa Angela, Bellizzi, Antonia, Bagorda, Anna, Guerra, Lorenzo, Tommasino, Massimo, Casavola, Valeria, Reshkin, Stephan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064074/
https://www.ncbi.nlm.nih.gov/pubmed/15535843
http://dx.doi.org/10.1186/bcr922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064074/
https://www.ncbi.nlm.nih.gov/pubmed/15535843
http://dx.doi.org/10.1186/bcr922

Ejemplares similares