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Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis

BACKGROUND: Epithelial mesenchymal transformation (EMT) in alveolar type 2 epithelial cells (AT2) is closely associated with pulmonary fibrosis (PF). Histone deacetylase 3 (HDAC3) is an important enzyme that regulates protein stability by modulating the acetylation level of non-histones. Here, we ai...

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Detalles Bibliográficos
Autores principales: Xiong, Rui, Geng, Boxin, Jiang, Wenyang, Hu, Yong, Hu, Zhaoyu, Hao, Bo, Li, Ning, Geng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640740/
https://www.ncbi.nlm.nih.gov/pubmed/37951958
http://dx.doi.org/10.1186/s13148-023-01588-5